Cookie Img
Send Inquiry Send SMS    Call Me Free Offline
Home » Products » Sodium Valproate » Sodium Valproate IP

Sodium Valproate IP

Sodium Valproate IP
Sodium Valproate IP
Product Code : CAS No - 1069-66-5
Product Description

With rich domain expertise, we have been consistently engaged in providing premium grade Sodium Valproate IP. This valproate is formulated using supreme grade chemical compounds and cutting edge methodology by deft professionals. Offered valproate is extensively demanded in pharmaceutical industry for making medicine used in the treatment of neurological disorder with epilepsy. This Sodium Valproate IP can be purchased from us at remarkable prices.  


Quality Key Points:

  • Non toxic
  • Stabilize electrical activity
  • Suitable for both adult and children
  • High effectiveness

 

 

Send Inquiry

 


Sodium Valproate IP

We are one of the reliable manufacturers and exporters of finest grade Sodium Valproate IP. Formulated using the latest techniques, this chemical is a sodium salt of valproic acid and is used for treating generalized epilepsy following in accordance to the seizure patters. Offered drug has excellent anti-epileptic and anti-convalsant properties, due to which it is widely used in the preperation of different typoes of drugs. We offer this Sodium Valproate IP to our esteemed clients in different packaging options to cater to their varied requirements at market leading prices.

Pharmacodynamic properties: The exact mode of action is still uncertain but the most likey mode of action is the potentiation of the inhibitory action of gamma amino butyric acid (GABA) through an action on the further synthesis or further metabolism of GABA.

Pharmacokinetic properties:

  • Protein binding: 90 to 95%
  • Metabolism: 75% by CYP enzyme
  • Half life: 9hrs- 18hrs
  • Excretion: Mainly excreted in urine following metabolism

Indications:

  • Absence
  • Myoclonic
  • Tonic-clonic
  • Atonic
  • Mixed

It is also indicated for partial epilepsy:   

  • Simple or complex seizures   
  • Secondary generalized seizures
Send Inquiry

Pharmacopoeial standards: Our Company has the license to manufacture sodium valproate of following pharmacopoeial standard:    

SODIUM VALPROATE BP/SODIUM VALPROATE IP

Product Name 2-propylpentanoic acid, sodium salt
Synonym Valproic acid, sodium salt
Molecular Formula C8 H15 Na O2
Molecular Weight 166.2 g / mole
CAS No. 1069-66-5
SPECIFICATIONS
 
 
1. Description A white or almost white crystalline powder, hygroscopic
2. Solubility Very soluble in water and in  ethanol (95%), practically insoluble in ether.
3. Identification (a) The infra red absorption  spectrum is concordant with the reference spectrum of sodium valproate. 
(b) The retention time of the principal peak in the chromatogram obtained with test solution correspondence to that of the principal peak in the  chromatogram obtained with the reference solution.
(c) Dence white precipitates is produced indicating test solution gives reaction of sodium salts.
4. Acidity and alkalinity 0.75 ml of either 0.1 M HCl or 0.1 M NaOH required to change the colour of the solution
5. Clarity & colour of the  solution 20% w/v solution is not more opalescent than opalescence of reference suspention II and is not more intensely coloured than reference solution Y6 
6. Heavy metal Not more than 20 ppm 
7. Chlorides Not more than 200 ppm
8. Sulphate Not more than 200 ppm
9. Related substances (a) Sum of the Total impurities not more than 0.3%
(b) Individual impurity not more than 0.1%
10. Loss on drying Not more than 2.00%
11. Assay (on dry basis) Between 98.5% to 101% calculated on dry basis.

ROAQ CHEMICALS PVT. LTD.

Contact Us

( *represents compulsory fields )

Tips on getting accurate quotes. Please include product name, order quantity, usage, special requests if any in your inquiry.



ROAQ CHEMICALS PVT. LTD.
41/B-5, GIDC, Estate, Behind Ashok Organics, Nandesari, Vadodara - 391340, Gujarat, India
Phone :+919069140240
Fax :91-265-2780181
Mr. Mukeshchandra Manubhai Patel (Director)
Mobile :+919069140240
Mr. Jaimin Patel
Mobile :+919069140240
Trust Stamp
Product Showcase
Send Inquiry Send SMS    Call Me Free